Strict Standards: Declaration of ContentController::display() should be compatible with JController::display($cachable = false) in
/home/h188220/old.ravazadeh.com/components/com_content/controller.php on line
373
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
71
Strict Standards: Non-static method JLoader::load() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
161
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
138
Deprecated: Non-static method JModel::addIncludePath() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/controller.php on line
382
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JPath::clean() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/model.php on line
253
Deprecated: Non-static method JRequest::getVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/content.php on line
35
Deprecated: Non-static method JHTML::_() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/controller.php on line
37
Strict Standards: Non-static method JLoader::load() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
161
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
138
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JPath::find() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/html/html.php on line
66
Deprecated: Non-static method JHTML::addIncludePath() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/html/html.php on line
66
Strict Standards: call_user_func_array() expects parameter 1 to be a valid callback, non-static method JHTMLBehavior::caption() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/joomla/html/html.php on line
91
Strict Standards: Non-static method JHTML::script() should not be called statically in
/home/h188220/old.ravazadeh.com/plugins/system/mtupgrade/behavior.php on line
86
Strict Standards: Non-static method JHTML::_() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/joomla/html/html.php on line
172
Strict Standards: call_user_func_array() expects parameter 1 to be a valid callback, non-static method JHTMLBehavior::mootools() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/joomla/html/html.php on line
91
Strict Standards: Non-static method JFactory::getConfig() should not be called statically in
/home/h188220/old.ravazadeh.com/plugins/system/mtupgrade/behavior.php on line
52
Strict Standards: Non-static method JHTML::script() should not be called statically in
/home/h188220/old.ravazadeh.com/plugins/system/mtupgrade/behavior.php on line
66
Strict Standards: Non-static method JURI::root() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/joomla/html/html.php on line
176
Strict Standards: Non-static method JFactory::getDocument() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/joomla/html/html.php on line
179
Strict Standards: Non-static method JFactory::getApplication() should not be called statically in
/home/h188220/old.ravazadeh.com/plugins/system/mtupgrade/behavior.php on line
70
Strict Standards: Non-static method JURI::root() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/joomla/html/html.php on line
176
Strict Standards: Non-static method JFactory::getDocument() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/joomla/html/html.php on line
179
Deprecated: Non-static method JRequest::getCmd() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/controller.php on line
40
Deprecated: Non-static method JRequest::getVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
255
Deprecated: Non-static method JRequest::_cleanVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
134
Deprecated: Non-static method JFilterInput::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
577
Deprecated: Non-static method JFactory::getUser() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/controller.php on line
46
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JFactory::getSession() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/factory.php on line
163
Deprecated: Non-static method JRequest::getVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/controller.php on line
47
Deprecated: Non-static method JRequest::_cleanVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
134
Deprecated: Non-static method JFilterInput::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
577
Deprecated: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in
/home/h188220/old.ravazadeh.com/libraries/joomla/filter/filterinput.php on line
512
Deprecated: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in
/home/h188220/old.ravazadeh.com/libraries/joomla/filter/filterinput.php on line
514
Deprecated: Non-static method JRequest::getVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/controller.php on line
48
Deprecated: Non-static method JRequest::_cleanVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
151
Deprecated: Non-static method JFilterInput::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
577
Deprecated: Non-static method JFactory::getDocument() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/controller.php on line
287
Deprecated: Non-static method JRequest::getCmd() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/controller.php on line
290
Deprecated: Non-static method JRequest::getVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
255
Deprecated: Non-static method JRequest::_cleanVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
134
Deprecated: Non-static method JFilterInput::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
577
Deprecated: Non-static method JRequest::getCmd() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/controller.php on line
291
Deprecated: Non-static method JRequest::getVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
255
Deprecated: Non-static method JRequest::_cleanVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
134
Deprecated: Non-static method JFilterInput::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
577
Strict Standards: Non-static method JLoader::load() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
161
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
138
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JPath::find() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/controller.php on line
627
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
71
Strict Standards: Non-static method JLoader::load() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
161
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
138
Deprecated: Non-static method JURI::base() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/view.php on line
178
Deprecated: Non-static method JHTML::addIncludePath() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/view.php on line
13
Deprecated: Non-static method JPath::clean() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/html/html.php on line
326
Deprecated: Non-static method JModel::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/controller.php on line
592
Strict Standards: Non-static method JLoader::load() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
161
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
138
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JPath::find() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/model.php on line
112
Deprecated: Non-static method JModel::addIncludePath() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/model.php on line
113
Deprecated: Non-static method JModel::_createFileName() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/model.php on line
114
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JFactory::getDBO() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/model.php on line
83
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JTable::addIncludePath() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/model.php on line
268
Deprecated: Non-static method JRequest::getVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/models/article.php on line
45
Deprecated: Non-static method JRequest::_cleanVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
134
Deprecated: Non-static method JFilterInput::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
577
Deprecated: Non-static method JFactory::getApplication() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/controller.php on line
356
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JMenu::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
705
Deprecated: Non-static method JError::isError() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
706
Deprecated: Non-static method JRegistryFormat::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/registry.php on line
373
Deprecated: Non-static method JFilterInput::clean() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/format.php on line
45
Deprecated: Non-static method JFactory::getCache() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/controller.php on line
307
Deprecated: Non-static method JFactory::getConfig() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/factory.php on line
192
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JCache::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/factory.php on line
208
Strict Standards: Non-static method JLoader::load() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
161
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
138
Strict Standards: Declaration of JCacheView::get() should be compatible with JCache::get($id, $group = NULL) in
/home/h188220/old.ravazadeh.com/libraries/joomla/cache/handler/view.php on line
150
Deprecated: Non-static method JRequest::getCmd() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/cache/cache.php on line
87
Deprecated: Non-static method JRequest::getVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
255
Deprecated: Non-static method JRequest::_cleanVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
151
Deprecated: Non-static method JFilterInput::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
577
Deprecated: Non-static method JRequest::getURI() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/cache/handler/view.php on line
148
Deprecated: Non-static method JFactory::getURI() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
51
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JURI::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/factory.php on line
403
Deprecated: Non-static method JCacheStorage::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/cache/cache.php on line
313
Deprecated: Non-static method JFactory::getConfig() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/cache/storage/file.php on line
37
Deprecated: Non-static method JError::isError() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/cache/cache.php on line
206
Deprecated: Non-static method JFactory::getDocument() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/cache/handler/view.php on line
85
Deprecated: Non-static method JFactory::getUser() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/views/article/view.html.php on line
33
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JFactory::getSession() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/factory.php on line
163
Deprecated: Non-static method JFactory::getDocument() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/views/article/view.html.php on line
34
Deprecated: Non-static method JDispatcher::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/views/article/view.html.php on line
35
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
71
Strict Standards: Non-static method JLoader::load() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
161
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
138
Deprecated: Non-static method JPathway::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
682
Deprecated: Non-static method JApplicationHelper::getClientInfo() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/pathway.php on line
75
Deprecated: Non-static method JSite::getMenu() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/includes/pathway.php on line
34
Deprecated: Non-static method JApplication::getMenu() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/includes/application.php on line
345
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JMenu::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
705
Deprecated: Non-static method JError::isError() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
706
Deprecated: Non-static method JError::isError() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
683
Deprecated: Non-static method JComponentHelper::getParams() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/includes/application.php on line
240
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JMenu::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
705
Deprecated: Non-static method JError::isError() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
706
Deprecated: Non-static method JFactory::getConfig() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
382
Deprecated: Non-static method JFactory::getConfig() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
382
Deprecated: Non-static method JRegistryFormat::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/registry.php on line
373
Deprecated: Non-static method JFilterInput::clean() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/format.php on line
45
Deprecated: Non-static method ContentHelperQuery::buildVotingQuery() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/models/article.php on line
526
Deprecated: Non-static method JFactory::getUser() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/models/article.php on line
608
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JFactory::getSession() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/factory.php on line
163
Deprecated: Non-static method JFactory::getDate() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/models/article.php on line
611
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
71
Deprecated: Non-static method JFactory::getLanguage() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/factory.php on line
427
Deprecated: Non-static method JLoader::register() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/factory.php on line
436
Strict Standards: Non-static method JLoader::load() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
161
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
138
Strict Standards: Non-static method JLoader::load() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
161
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
138
Deprecated: Non-static method JFactory::getACL() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/user/user.php on line
260
Deprecated: Non-static method JText::_() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/models/article.php on line
550
Deprecated: Non-static method JFactory::getLanguage() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/methods.php on line
120
Deprecated: Non-static method JFactory::getUser() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/models/article.php on line
110
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JFactory::getSession() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/factory.php on line
163
Deprecated: Non-static method JRequest::getVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/models/article.php on line
583
Deprecated: Non-static method JRequest::_cleanVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
151
Deprecated: Non-static method JFilterInput::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
577
Deprecated: Non-static method JRequest::getVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/views/article/view.html.php on line
60
Deprecated: Non-static method JRequest::_cleanVar() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
151
Deprecated: Non-static method JFilterInput::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/environment/request.php on line
577
Deprecated: Non-static method JTable::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/models/article.php on line
181
Strict Standards: Non-static method JLoader::load() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
161
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
138
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JPath::find() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/database/table.php on line
91
Deprecated: Non-static method JTable::addIncludePath() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/database/table.php on line
91
Deprecated: Non-static method JFactory::getDBO() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/database/table.php on line
112
Deprecated: Non-static method JFactory::getACL() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/user/user.php on line
260
Deprecated: Non-static method JFactory::getACL() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/user/user.php on line
260
Deprecated: Non-static method JFactory::getACL() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/user/user.php on line
260
Deprecated: Non-static method JRoute::_() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/views/article/view.html.php on line
78
Deprecated: Non-static method ContentHelperRoute::getArticleRoute() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/views/article/view.html.php on line
78
Deprecated: Non-static method ContentHelperRoute::_findItem() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/helpers/route.php on line
49
Deprecated: Non-static method JComponentHelper::getComponent() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/helpers/route.php on line
97
Deprecated: Non-static method JComponentHelper::_load() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/helper.php on line
39
Deprecated: Non-static method JApplication::getMenu() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/helpers/route.php on line
99
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JMenu::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
705
Deprecated: Non-static method JError::isError() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
706
Deprecated: Non-static method JFactory::getApplication() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/methods.php on line
41
Deprecated: Non-static method JFactory::getConfig() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/includes/application.php on line
372
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JRouter::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
659
Deprecated: Non-static method JError::isError() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
660
Deprecated: Non-static method JSite::getMenu() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/includes/router.php on line
419
Deprecated: Non-static method JApplication::getMenu() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/includes/application.php on line
345
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JMenu::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
705
Deprecated: Non-static method JError::isError() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
706
Deprecated: Non-static method JFactory::getApplication() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/includes/router.php on line
401
Deprecated: Non-static method JSite::getMenu() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/includes/router.php on line
295
Deprecated: Non-static method JApplication::getMenu() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/includes/application.php on line
345
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JMenu::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
705
Deprecated: Non-static method JError::isError() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
706
Strict Standards: Non-static method JSite::getMenu() should not be called statically in
/home/h188220/old.ravazadeh.com/components/com_content/router.php on line
19
Strict Standards: Non-static method JApplication::getMenu() should not be called statically in
/home/h188220/old.ravazadeh.com/includes/application.php on line
345
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JMenu::getInstance() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
705
Strict Standards: Non-static method JError::isError() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
706
Deprecated: Non-static method JFactory::getApplication() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/includes/router.php on line
90
Deprecated: Non-static method JFactory::getConfig() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
382
Deprecated: Non-static method JFactory::getConfig() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
382
Deprecated: Non-static method JURI::base() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/includes/router.php on line
109
Deprecated: Non-static method JPluginHelper::importPlugin() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/components/com_content/views/article/view.html.php on line
101
Deprecated: Non-static method JPluginHelper::_load() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
92
Deprecated: Non-static method JPluginHelper::_import() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
97
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JDispatcher::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
140
Deprecated: Non-static method JPluginHelper::getPlugin() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
147
Deprecated: Non-static method JPluginHelper::_load() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
41
Deprecated: Non-static method JComponentHelper::getParams() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/plugins/content/labels.php on line
35
Deprecated: Non-static method JComponentHelper::getComponent() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/helper.php on line
83
Deprecated: Non-static method JComponentHelper::_load() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/component/helper.php on line
39
Deprecated: Non-static method JRegistryFormat::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/registry.php on line
373
Deprecated: Non-static method JFilterInput::clean() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/format.php on line
45
Deprecated: Non-static method JFactory::getDBO() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/plugins/content/labels.php on line
37
Deprecated: Non-static method JFactory::getConfig() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/plugins/content/labels.php on line
38
Deprecated: Non-static method JPluginHelper::_import() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
97
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JDispatcher::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
140
Deprecated: Non-static method JPluginHelper::getPlugin() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
147
Deprecated: Non-static method JPluginHelper::_load() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
41
Deprecated: Non-static method JPluginHelper::getPlugin() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/plugins/content/cdaccesstext.php on line
41
Deprecated: Non-static method JPluginHelper::_load() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
41
Deprecated: Non-static method JRegistryFormat::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/registry.php on line
373
Deprecated: Non-static method JFilterInput::clean() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/format.php on line
45
Deprecated: Non-static method JPluginHelper::_import() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
97
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JDispatcher::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
140
Deprecated: Non-static method JPluginHelper::getPlugin() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
147
Deprecated: Non-static method JPluginHelper::_load() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
41
Deprecated: Non-static method JPluginHelper::_import() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
97
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JDispatcher::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
140
Deprecated: Non-static method JPluginHelper::getPlugin() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
147
Deprecated: Non-static method JPluginHelper::_load() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
41
Deprecated: Non-static method JRegistryFormat::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/registry.php on line
373
Deprecated: Non-static method JFilterInput::clean() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/format.php on line
45
Deprecated: Non-static method JPluginHelper::_import() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
97
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JDispatcher::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
140
Deprecated: Non-static method JPluginHelper::getPlugin() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
147
Deprecated: Non-static method JPluginHelper::_load() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
41
Deprecated: Non-static method JRegistryFormat::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/registry.php on line
373
Deprecated: Non-static method JFilterInput::clean() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/format.php on line
45
Deprecated: Non-static method JHTML::addIncludePath() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/plugins/content/comments.php on line
54
Deprecated: Non-static method JPath::clean() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/html/html.php on line
326
Deprecated: Non-static method JPluginHelper::_import() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
97
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JDispatcher::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
140
Deprecated: Non-static method JPluginHelper::getPlugin() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
147
Deprecated: Non-static method JPluginHelper::_load() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
41
Deprecated: Non-static method JRegistryFormat::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/registry.php on line
373
Deprecated: Non-static method JFilterInput::clean() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/registry/format.php on line
45
Deprecated: Non-static method JPluginHelper::_import() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
97
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JDispatcher::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
484
Deprecated: Non-static method JDispatcher::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
140
Strict Standards: Non-static method JLoader::load() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
161
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
138
Deprecated: Non-static method JPluginHelper::_import() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
97
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JDispatcher::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
484
Deprecated: Non-static method JDispatcher::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
140
Strict Standards: Non-static method JLoader::load() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
161
Strict Standards: Non-static method JLoader::register() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
138
Deprecated: Non-static method JPluginHelper::_import() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/plugin/helper.php on line
97
Strict Standards: Non-static method JLoader::import() should not be called statically in
/home/h188220/old.ravazadeh.com/libraries/loader.php on line
186
Deprecated: Non-static method JDispatcher::getInstance() should not be called statically, assuming $this from incompatible context in
/home/h188220/old.ravazadeh.com/libraries/joomla/application/application.php on line
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 شواهد قبلی مطرح کننده آن هستند که بتابلوکرها، دیورتیک ها و استاتین ها خطر ایجاد دیابت جدید را افزایش میدهند. در این تحلیل مجدد روی داده های کارآزمایی تصادفی شده شاهددار NAVIGATOR، پژوهشگران به ارزیابی این نکته پرداخته اند که آیا مصرف بتابلوکرها، دیورتیک های تیازیدی، استاتین ها یا کلسیم بلوکرها در بیش از 9300 بیمار مبتلا به اختلال تحمل گلوکز و عوامل خطر قلبی – عروقی با ایجاد دیابت جدید همراهی دارد یا خیر.
طی دوره پیگیری با میانه مدت 5 سال، بتابلوکرها، دیورتیک های تیازیدی، استاتین های و کلسیم بلوکرها هر کدام برای 20% از بیمارانی که قبلاً با آنها مواجهه نداشتند، شروع شدند. پس از تعدیل از نظر متغیرهای مختلف، خطر ایجاد دیابت جدید در بیمارانی که برایشان دیورتیک (نسبت زیان 2/1) یا استاتین (نسبت زیان 5/1) شروع شده بود، به صورت معنی داری بیش از دیگران بود. تعداد مورد نیاز برای زیان (NNH) برای دیورتیک 17 نفر (یعنی از 17 نفری که دیورتیک برایشان شروع شد، یک نفرشان دیابت گرفتند) و برای استاتین 12 نفر بود. خطر ایجاد دیابت با مصرف بتا بلوکرها یا کلسیم بلوکرها ارتباطی نداشت. BMJ December 9, 2013.
رهنمود: پژوهشگران این مطالعه توصیه کرده اند که در صورت شروع دیورتیک های تیازیدی و استاتین ها برای بیماران پرخطر از نظر ابتلا به دیابت، قند خون باید مرتبا پایش شود. طراحی این مطالعه به نحوی بوده که امکان دخالت عوامل مخدوش کننده در آن وجود دارد ولی این همراهی در چند مطالعه جدید دیگر نیز گزارش شده است. با وجود این، در بیماران منتخب احتمالاً منافع مصرف این داروها بر این خطر خواهد چربید.
Mueller PS. Diuretics and statins are Associated with New-Onset Diabetes. Journal Watch General Medicine January 14, 2014.
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آیا می دانید که دیورتیک ها و استاتین ها خطر ایجاد دیابت جدید را افزایش میدهند
شواهد قبلی مطرح کننده آن هستند که بتابلوکرها، دیورتیک ها و استاتین ها خطر ایجاد دیابت جدید را افزایش میدهند. در این تحلیل مجدد روی داده های کارآزمایی تصادفی شده شاهددار NAVIGATOR، پژوهشگران به ارزیابی این نکته پرداخته اند که آیا مصرف بتابلوکرها، دیورتیک های تیازیدی، استاتین ها یا کلسیم بلوکرها در بیش از 9300 بیمار مبتلا به اختلال تحمل گلوکز و عوامل خطر قلبی – عروقی با ایجاد دیابت جدید همراهی دارد یا خیر.
طی دوره پیگیری با میانه مدت 5 سال، بتابلوکرها، دیورتیک های تیازیدی، استاتین های و کلسیم بلوکرها هر کدام برای 20% از بیمارانی که قبلاً با آنها مواجهه نداشتند، شروع شدند. پس از تعدیل از نظر متغیرهای مختلف، خطر ایجاد دیابت جدید در بیمارانی که برایشان دیورتیک (نسبت زیان 2/1) یا استاتین (نسبت زیان 5/1) شروع شده بود، به صورت معنی داری بیش از دیگران بود. تعداد مورد نیاز برای زیان (NNH) برای دیورتیک 17 نفر (یعنی از 17 نفری که دیورتیک برایشان شروع شد، یک نفرشان دیابت گرفتند) و برای استاتین 12 نفر بود. خطر ایجاد دیابت با مصرف بتا بلوکرها یا کلسیم بلوکرها ارتباطی نداشت. BMJ December 9, 2013.
رهنمود: پژوهشگران این مطالعه توصیه کرده اند که در صورت شروع دیورتیک های تیازیدی و استاتین ها برای بیماران پرخطر از نظر ابتلا به دیابت، قند خون باید مرتبا پایش شود. طراحی این مطالعه به نحوی بوده که امکان دخالت عوامل مخدوش کننده در آن وجود دارد ولی این همراهی در چند مطالعه جدید دیگر نیز گزارش شده است. با وجود این، در بیماران منتخب احتمالاً منافع مصرف این داروها بر این خطر خواهد چربید.
Mueller PS. Diuretics and statins are Associated with New-Onset
منبع: نشریه نوین پزشکی|شماره 567| 1 اسفند 92
Diabetes. Journal Watch General Medicine January 14, 2014.
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